Dr. Kenton Bruice MD

Women's Health

PMS & PMDD — Hormonal Treatment in Denver

Premenstrual syndrome (PMS) and PMDD are driven by hormonal fluctuations — particularly progesterone deficiency and estrogen volatility in the luteal phase. Dr. Bruice addresses the root cause rather than masking symptoms.

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Common Signs & Symptoms

  • !Mood swings, irritability, or rage in the luteal phase
  • !Anxiety and depression worsening premenstrually
  • !Breast tenderness
  • !Bloating and water retention
  • !Food cravings
  • !Fatigue
  • !Headaches
  • !Symptoms resolving with menstruation

What Causes This?

  • Progesterone deficiency in the luteal phase
  • Estrogen excess relative to progesterone
  • Serotonin sensitivity to progesterone metabolites
  • Magnesium and B6 deficiency amplifying symptoms

Treatment Approaches

Luteal Phase Progesterone

Cyclic progesterone in the second half of the cycle directly addresses the hormonal cause of PMS/PMDD.

Magnesium & B6

Magnesium deficiency amplifies PMS — supplementation reduces symptoms significantly.

Estrogen Stabilization

For severe PMDD, continuous low-dose estrogen to prevent the luteal estrogen drop.

Frequently Asked Questions

Is PMDD just bad PMS?

PMDD is more severe — with symptoms that significantly impair functioning. Both are hormonally driven and both respond to progesterone therapy.

Related Topics

Think This Could Be Your Issue?

A proper diagnosis is the first step. Schedule your consultation today.

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