Low testosterone in men is referred to as Low Testosterone in Men. As men age their testosterone and DHEA levels decline. The most common symptoms of Low Testosterone in Men are fatigue, loss of libido, erectile dysfunction, abdominal weight gain, and loss of motivation or zest for life. Other common symptoms are mood changes, sleep problems, and reduced muscle mass. Dr. Bruice has been treating Low Testosterone in Men with bioidentical testosterone and DHEA since 1998. Dr. Bruice prescribes testosterone creams, injections, or pellets.

Between the ages of 25 and 50, testosterone levels decrease by aapproximately 50%. In addition, older men produce larger quantities of aromatase, causing them to convert more of their testosterone to estrogens. Declining testosterone predisposes a man to weight gain. Weight gain increases estrogens and estrogens increase sex hormone binding globulin which inactivates testosterone, leading to more weight gain. Once these hormones are balanced properly, a man is then able to lose weight. Indole-3-carbinol helps to balance estrogen metabolism.

For many years, it was thought that any increase in testosterone levels contributed to the risk of prostate cancer. This fear spurred significant controversy over the use of testosterone therapy. However, a recent review of the relevant medical literature, published in the "New England Journal of Medicine", concluded that testosterone therapy is not associated with an increase rate of prostate cancer, or any other prostate illness. Prostate cancer actually becomes more prevalent exactly at the time in a man's life when testosterone levels decline. A 2002 study published in the "International Journal of Andrology" claims that testosterone therapy may even benefit prostate health.
Prior to prescribing testosterone it is important to check both free and total testosterone levels. This is done by blood draw, preferably in the morning. It is important to also check estradiol levels. Estradiol is a "female" hormone that can be converted from testosterone by the enzyme aromatase. As men age, they experience an increase in aromatase activity, thus their estradiol levels rise. This is why older men have an greater risk of prostate cancer. Testosterone is not bad for the prostate, but the metabolites of testosterone (estradiol and dihyrotestosterone (DHT)) can be harmful to the prostate.