Reviewed by Dr. Kenton Bruice, MD
Reading time: three minutes
As men reach their 40s and 50s, testosterone and growth hormone levels naturally decline. This hormonal shift can slow metabolism, reduce muscle mass, and drain energy, even in men who stay active and eat well.
This blog explains why these changes happen, how they affect strength and body composition, and what you can do to maintain muscle and vitality over time.
Table of Contents
Key Takeaway
Declining testosterone and growth hormone can lead to muscle loss and fatigue. With proper testing and treatment, you can maintain strength, energy and vitality as you age.
The Role of Testosterone and Growth Hormone in Muscle Maintenance
Testosterone and human growth hormone are essential for building and preserving muscle. They regulate protein synthesis, support fat metabolism, and help maintain steady energy levels.
During your 20s and early 30s, these hormones stay high enough to sustain muscle with less effort. As you reach your late 30s and 40s, production gradually decreases.
Over time, this decline can lead to slower recovery, reduced strength, and a noticeable shift in body composition.
- Testosterone drives muscle growth, strength, mental clarity, and motivation.
- Human growth hormone (HGH) supports tissue repair, fat burning, and joint health.
When levels fall, protein turnover slows, muscle repair becomes less efficient, and fat gain can increase.
These changes often happen gradually. Many men notice their usual training and nutrition are no longer enough to maintain the same results. Evaluating hormone levels can be an important step in understanding why progress stalls and what solutions are available.
What Hormone Changes Mean for Your Body
Hormonal shifts in midlife affect far more than muscle. They influence how your body uses nutrients, adapts to exercise, and manages daily stress.
Over time, you might notice:
- Slower recovery after workouts
- Muscle gradually decreasing, even with regular training
- More fat accumulating around your midsection
- Less energy and motivation
- Disrupted sleep and occasional mental fog
- Changes in libido and sexual performance
These changes are linked to a slower metabolism and less effective muscle repair. Over time, this combination can make it harder to stay lean, strong, and energized.
Four Strategies to Preserve Muscle and Energy as You Age
You do not have to settle for decline. You just need the right tools to work with your body as it changes.
Strength Train With Purpose
Prioritize compound lifts like squats, presses, and pulls. Stick with progressive overload and allow for longer recovery between sessions. Consistency matters more now than intensity.
Boost Protein and Nutrients
Aim for at least 1 gram of protein per pound of body weight daily. Add nutrients that support muscle and hormone health, especially vitamin D, magnesium, zinc, and omega-3s. Creatine can also help maintain strength and recovery.
Check Your Testosterone
Testosterone is central to strength, muscle maintenance, and energy. Dr. Bruice offers thorough lab evaluations to measure total and free testosterone and related markers. If your levels are low, he can walk you through options like pellets or injections and help you decide whether replacement therapy fits your goals.
Learn More About Hormone Therapy for Men
Evaluate Growth Hormone Levels
Growth hormone supports recovery, fat metabolism, and lean muscle. Dr. Bruice can test IGF-1 to gauge your growth hormone status. When levels are below optimal, peptide therapy may be considered to help your body produce more of its own growth hormone naturally.
When to Get Evaluated
If you have noticed more belly fat, softer muscle tone, slower recovery, or a drop in energy and motivation, it may be time to check your hormone levels. Early evaluation can help you understand what is changing and take steps to address it.
Comprehensive lab testing and a detailed consultation with Dr. Bruice can determine whether hormones are playing a role and whether any treatment makes sense for your health goals.
Schedule a Hormone Evaluation in St. Louis
Dr. Kenton Bruice provides comprehensive hormone testing and personalized treatment plans to help men regain strength, energy, and metabolic health. From testosterone replacement therapy to HGH peptide options, his approach is tailored to your individual needs and goals.
To book an appointment with Dr. Bruice at the St. Louis Hormone Institute of Missouri, call (314) 222-7567 or visit us at 9909 Clayton Rd, Suite 225, St. Louis, MO.
Other locations
๐Denver Hormone Institute of Colorado
55 Madison Street, Suite 575 Denver, CO
FAQs
Which is better, TRT pellets or injections?
Testosterone replacement therapy can be delivered through pellets or injections, and both are effective. Pellets are implanted under the skin and release testosterone steadily over several months, offering convenience and consistent levels. Injections are given weekly or biweekly, allowing for more precise control and easier dose adjustments. The choice depends on your lifestyle and preferences.
How long does it take to feel results from testosterone therapy?
Many men start to notice improvements in energy, mood, and focus within a few weeks. Changes in muscle mass, body composition, and strength usually take a few months to develop more fully.
Are HGH peptides the same as synthetic growth hormone?
No, they are not the same. HGH peptides help your body release more of its own natural growth hormone, while synthetic HGH replaces it directly. Peptides have a lower risk profile and work gradually to support muscle recovery, metabolism, and overall vitality.